🍷 Winery

Safehouse Winery

Syracuse, Nebraska

Small Syracuse winery pouring Nebraska wines Saturday afternoons — an intimate, inexpensive tasting room in Otoe County wine country.

City Syracuse, NE
Region Otoe County
Address 325 5th St, Syracuse, NE 68446
Website Visit site →
Instagram @safehousewinery
Tasting room hours Sat 4-8pm
Wine Trail Yes ✓

Safehouse is the anti-destination winery, and that’s its charm: a small tasting room in Syracuse pouring Nebraska wines on Saturday afternoons, inexpensive and unpretentious. No event center, no glamping, no pretense — just wine, poured by people who made it.

In a county that also hosts Rich Harvest’s bigger operation a mile north of town, Safehouse is the intimate alternative: the tasting room you stumble into and end up staying. The limited hours (Saturdays 4 to 8) make it feel like a secret, even though it isn’t.

Pair it with Rich Harvest for a two-stop Syracuse wine afternoon — big and small, same town.

Frequently asked questions

Where is Safehouse Winery?

Safehouse Winery is in Syracuse, Nebraska. The address is 325 5th St, Syracuse, NE 68446.

Is Safehouse Winery on the Nebraska Wine Trail?

Yes — Safehouse Winery is on the Nebraska Wine Trail.

What wines does Safehouse Winery make?

Expect cold-hardy Nebraska hybrids; ask what’s pouring when you visit.

Last updated October 2026 · TrueNebraska.com

← Back to all wineries